Research development in tumor therapy: role of iron-related nanoparticles

As an essential nutrient element for life, iron’s metabolic balance in body tissues is crucial to sustaining normal physiological functions, and it inextricably related tumors. Nanotechnology gaining much attention around the world cancer treatment. Considering critical role of iron metabolism, nanocarriers’ toxicity biocompatibility, novel nanomaterials based on biochemical activity regulatory proteins homeostasis-metabolism show broad application prospects field tumor diagnosis In this review, iron-related nanocarriers therapy, such as oxide nanoparticles, Fe-based metal-organic frameworks, ferritin, transferrin, was reviewed, aiming help people better understand their tremendous potential therapy.